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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOPEY2 All Species: 32.12
Human Site: S601 Identified Species: 54.36
UniProt: Q9Y3R5 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3R5 NP_005119.2 2298 258184 S601 S A S S P E L S E H L R V P R
Chimpanzee Pan troglodytes XP_531552 2298 258112 S601 S A S S P E L S E H L R V P R
Rhesus Macaque Macaca mulatta XP_001084653 2286 256620 S589 S A S S P E L S E H L R V P R
Dog Lupus familis XP_544874 2297 257913 S601 S A S S P E L S E H L R V P R
Cat Felis silvestris
Mouse Mus musculus Q3UHQ6 2295 257491 S601 S A S S P E L S E H L R V P R
Rat Rattus norvegicus XP_001055500 2294 257490 S600 S A S S P E L S E H L R V P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512569 2247 251024 S601 S A S S P E L S Q H L T G P R
Chicken Gallus gallus XP_001232723 2283 257889 S599 S A S S P E L S Q H L G V P T
Frog Xenopus laevis Q642P2 2270 256829 P597 I G L S A S S P E L S K H L R
Zebra Danio Brachydanio rerio NP_956904 817 86774
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZBE8 2599 291169 S624 S E L D K D I S A S D T G Q Q
Honey Bee Apis mellifera XP_395999 2434 273219 R588 N S G G A T K R S D K K S K K
Nematode Worm Caenorhab. elegans Q9XW10 2417 267134 N678 L G F G I V D N P G D Y C R E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03921 1698 194669 P88 S S L S P A L P A G V H Q K T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.8 89.9 N.A. 86.4 86.4 N.A. 73.9 75.2 69 21.9 N.A. 27.6 32.1 22.3 N.A.
Protein Similarity: 100 99.7 96 94.6 N.A. 92.4 92.5 N.A. 83 85.4 82 28.7 N.A. 47 53.2 40.9 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 80 80 20 0 N.A. 13.3 0 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 86.6 26.6 0 N.A. 33.3 26.6 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 58 0 0 15 8 0 0 15 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 8 0 8 8 0 0 8 15 0 0 0 0 % D
% Glu: 0 8 0 0 0 58 0 0 50 0 0 0 0 0 8 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 15 8 15 0 0 0 0 0 15 0 8 15 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 58 0 8 8 0 0 % H
% Ile: 8 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 0 8 0 0 0 8 15 0 15 8 % K
% Leu: 8 0 22 0 0 0 65 0 0 8 58 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 65 0 0 15 8 0 0 0 0 58 0 % P
% Gln: 0 0 0 0 0 0 0 0 15 0 0 0 8 8 8 % Q
% Arg: 0 0 0 0 0 0 0 8 0 0 0 43 0 8 58 % R
% Ser: 72 15 58 72 0 8 8 65 8 8 8 0 8 0 0 % S
% Thr: 0 0 0 0 0 8 0 0 0 0 0 15 0 0 15 % T
% Val: 0 0 0 0 0 8 0 0 0 0 8 0 50 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _